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"The approximately 25,000-year-old paintings "The Dappled Horses of Pech-Merle" depict spotted horses on the walls of a cave in France remarkably similar to a pattern known as "leopard" in modern horses such as Appaloosas. Horses were popular among Stone Age artists, found in most cave paintings that have recognizable animals in them, commonly in a caricature form that slightly exaggerates the most typical "horsey" features, such as their manes of hair."
via livescience.com